Comments on: Why Do We Age?

By: drebanks

drebanks — Tue, 18 Jan 2011 01:18:32 +0000

Thanks for the interesting comments. Another telomerase activator to consider is Cycloastragenol extracted and studied by a biotech firm named Geron Corporation. It’s telomerase activating properties were confirmed in research at UCLA.

By: jeffrey dach md

jeffrey dach md — Wed, 08 Dec 2010 13:18:26 +0000

There is really no need for genetic engineering to activate telomerase as was done in the Depinho mouse model. There is about 20 years of research on Telomere activation. There are two receptors for estrogen on the TERT gene which controls this process. Whether you happen to be a human being or a mouse, the best way to increase telomerase activity, lengthen the telomeres and reverse aging is with the human bioidentical hormone, 17-Beta-Estradiol, also known as estrogen. In 1999, Kyo demonstrated that 17-Beta-Estradiol activates telomerase via direct and indirect effects on the hTERT promoter region. This was confirmed in 2000 by Silvia Misiti and again in 2009 by Rodrigo T. Calado from the NIH.

A recent December 2010 study from Imanishi from Japan showed that 17-Beta-Estradiol (estrogen) augments telomerase activity, thereby accelerating recovery after injury and reducing the effects of aging (reducing senescence).

Natural substances such as resveratrol, gingko and silymarin also activate telomeres.

For more see:

http://jeffreydach.com/2010/12/03/anti-aging-breakthrough-with-telomerase-knockout-mice-by-jeffrey-dach-md.aspx

regards, jeffrey dach md

By: Are You Losing Muscle Mass? « Alternity

Are You Losing Muscle Mass? « Alternity — Fri, 24 Sep 2010 20:48:36 +0000

[...] study demonstrated that long term regular exercise was associated with improved preservation of telomere length, which determines aging at a cellular level.[5] Proper mitochondrial function is also crucial for [...]

By: drebanks

drebanks — Tue, 27 Jul 2010 18:56:45 +0000

I am glad you found the information useful. What additional information would you like to know?

By: Bob Goddard

Bob Goddard — Mon, 26 Jul 2010 18:41:02 +0000

I have known about telemeres since Alan Alder did a program on the Diccovery Chanel I would like to know more about them. E-mail bkgoddard@sbcglobal.net. Thanks